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Will combine GSK's Mekinist with Pfizer's investigational palbociclib
November 21, 2013
By: Gil Roth
President, Pharma & Biopharma Outsourcing Association
Pfizer and GSK have entered into an agreement to explore the anti-cancer efficacy and the safety of GSK’s trametinib (GSK1120212) combined with Pfizer’s palbociclib (PD-0332991) in a Phase I/II study (Study 200344) in patients with advanced/metastatic melanoma. The study is a dose-escalation, open-label study designed to determine the recommended combination regimen (RCR) for trametinib plus palbociclib in patients with melanoma. The study will also evaluate the effect of the combination on tum...
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